Secoverine hydrochloride is a muscarinic antagonist in human isolated gastrointestinal muscle and myometrium
Sanger, G.J.; Bennett, A.
Journal of Pharmacy and Pharmacology 33(11): 711-714
1981
ISSN/ISBN: 0022-3573 PMID: 6118409 Document Number: 177740
Secoverine is a new antimuscarinic agent selective for smooth muscle. It is a potent anticholinergic antagonist of acetylcholine in strips of human gastrointestinal and uterine muscle. The pA2 values in gut longitudinal and circular muscle, and myometrium were 9.1, 9.3 and 8.6, respectively.
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