Effects of p-phenylenediamine on lung function and health-related quality of life of workers
Zhang, M.; Fan, L.; Liu, B.F.; Lin, J.; Tang, H.J.; Zhu, B.L.; Miao, R.M.; Fang, X.L.; Fang, J.Y.; Zhao, S.L.; Zhang, M.B.; Zeng, Q.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 36(11): 834-836
2019
ISSN/ISBN: 1001-9391 PMID: 30646647 Document Number: 17688
Objective To study the effects p-phenylenediamine (PPD) on lung function and healthrelated quality of life of occupational exposed workers. Methods This study was based on data from a company that produce hair dye containing PPD in China. Workers who exposed to PPD were selected as the study group, and workers un-exposed to PPD were selected as the control group. Questionnaires on health-related quality of life of workers using the 36-item Short Form Health Survey (SF-36). Occupational health examination assessment results were tested in Taizhou Cancer Hospital. The lung function test includes forced vital capacity (FVC), forced expiratory volume in one second (FEV io), and ratio of FEVio to FVC (FEV1JFVC). Results The difference in systolic blood pressure between the PPD exposed group and the control group was statistically significant (P<0.05). FVC, FEN/if), and FEV,JFVC of the lung function indexes in the exposed group were lower than those in the control group (P<0.05). In the health-related quality of life, body pain (P=0.002), general health (P=0.029), vitality (P=0.038), and mental health (P=0.003) were lower in the exposed group than in the control group. Conclusion Occupational exposed to PPD may induce hazard to the workers' lung function and may cause detrimental effect on workers' health-related quality of life.
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