The theory of sets as a tool in systematic drug design
Austel, V.; Kutter, E.
Arzneimittel-Forschung 31(1a): 130-135
1981
ISSN/ISBN: 0004-4172 PMID: 7195204 Document Number: 176262
A strategy of practical drug design is developed on the basis of the theory of sets. This strategy accounts for the fact that new drugs are required to optimally approach a certain activity profile rather than showing maximal intrinsic activity. In addition, modern structure selection techniques as well as qualitative and quantitative structure-activity relationships are incorporated in the strategy so as to optimally contribute to an economical use of experimental capacity.