Comparison and analysis of the therapeutic effect of different statins in the treatment of atherosclerosis
Liu, M.; Liu, G.; Wang, M.
Pakistan Journal of Pharmaceutical Sciences 31(4(Special): 1737-1742
2018
ISSN/ISBN: 1011-601X PMID: 30203772 Document Number: 17623
Studies have confirmed that lipid-lowering drugs can effectively control the morbidity and mortality of cardiovascular and cerebrovascular diseases and statins are the most widely used. The aim of this study is to investigate the effect and mechanism of different statins on atherosclerotic patients. The patients were randomly divided into 4 groups according to the digital method, and the patients were treated with conventional therapy, simvastatin treatment, pravastatin treatment, atorvastatin treatment. It is concluded that statins are safe, effective and reliable for the treatment of atherosclerosis, and worthy of clinical promotion. The results also showed that after 6 months of taking statins, the levels of NO and NOS increased, the thickness of carotid intima-media became thinner and the plaque score decreased. This study provides a basis for elucidating the role of statins in the body.
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