Top Abstract Purchase Preview Related
Home
>
Node
>
Subnode

Vismodegib and the Hedgehog Pathway Inhibitors: a Historical Perspective to Current Clinical Application

Tang, J.C.; Hanke, C.W.; Caro, I.

Journal of Drugs in Dermatology Jdd 17(5): 506-508

2018

ISSN/ISBN: 1545-9616
PMID: 29742180
Document Number: 17604
Vismodegib (Erivedge, Genentech-Roche) is the first in class of Hedgehog pathway inhibitors approved for treatment of metastatic basal cell carcinoma (BCC), or locally advanced BCC that has recurred after surgery or is not amenable to surgery or radiation. Its path to discovery has been unique and traces its origin to corn lilies, sheep, Drosophila flies, and the Hedgehog signaling pathway.

Document emailed within 1 workday
Secure & encrypted payments

Vismodegib and the Hedgehog Pathway Inhibitors: a Historical Perspective to Current Clinical Application

Eggertsen, S.C.; Bergman, J.J. 1983: Breast self-examination: historical perspective and current progress Journal of Family Practice 16(4): 713-716
Chhabra, A.; Chhabra, N.; Makkar, S.; Sharma, A. 2011: The controversial issue of centric relation: a historical and current dental perspective? Minerva Stomatologica 60(10): 543-549
Azurmendi, P. 2016: Organogenesis regulation by Hedgehog signaling pathway Medicina 76(4): 258-260
Lesiak, A.; Sysa-Jedrzejowska, A.; Narbutt, J. 2010: The role of sonic hedgehog pathway in skin carcinogenesis Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego 29(170): 141-143
Hofmann, B. 1993: Birth of clinical practice--in a historical perspective Tidsskrift for den Norske Laegeforening: Tidsskrift for Praktisk Medicin Ny Raekke 113(29): 3575-3577
Geeraert, P.; Williams, J.S.; Brownell, I. 2013: Targeting the hedgehog pathway to treat basal cell carcinoma Journal of Drugs in Dermatology: Jdd 12(5): 519-523
Guldemann, T.; Stoneking, M. 2008: A Historical Appraisal of Clicks : A Linguistic and Genetic Population Perspective - Une évaluation historique des claquements : une perspective linguistique et de génétique des populations Annual Review of Anthropology 37: 93-109
Hanke, C.W.; Mhatre, S.K.; Oliveri, D.; Zivkovic, M.; Caro, I.; Bergström, D.; Dawson, K.; Sima, C.S. 2018: Vismodegib use in Clinical Practice: Analysis of a United States Medical Claims Database Journal of Drugs in Dermatology: Jdd 17(2): 143-148
Hayashi, T.; Suzuki, K. 1993: Molecular biology of protein C-thrombomodulin pathway. Structure and function, and basic studies on its clinical application Nihon Rinsho. Japanese Journal of Clinical Medicine 51(6): 1610-1619
Nakayama, S.; Koide, H. 1991: Clinical application of proteinase inhibitors to renal diseases Nihon Rinsho. Japanese Journal of Clinical Medicine 49(9): 2109-2114
Spierenburg, P. 2008: Carroll (Stuart) (ed.), Cultures of Violence. Interpersonal Violence in Historical Perspective / Watson (Katherine D.) (ed.), Assaulting the Past. Violence and Civilization in Historical Context Crime, Histoire-Sociétés 12(1): 128-130
Gomez Portilla, A.; Deraco, M.; Sugarbaker, P.H. 1997: Clinical pathway for peritoneal carcinomatosis from colon and rectal cancer: guidelines for current practice Tumori 83(4): 725-728
Hunter, M. 2005: Cultural politics and masculinities : Multiple-partners in historical perspective in KwaZulu-Natal - Politique culturelle et masculinités: partenaires multiples dans une perspective historique au ZwaZulu-natal Culture, Health and Sexuality 7(4): 389-403
Verburg, A.F.E.; van den Donk, M.; Wiersma, T. 2019: Application of new glucose lowering drugs: DPP-4 inhibitors, GLP-1 receptor agonists and SGLT-2 inhibitors Nederlands Tijdschrift Voor Geneeskunde 163
Ma, X. 2014: Review and perspective for clinical investigation and application of oro-maxillofacial cone beam computed tomography in China Zhonghua Kou Qiang Yi Xue Za Zhi 49(1): 2-4
Christofferson, R. 1998: Angiogenesis inhibitors in advanced cancer. many current clinical trials show promising results Lakartidningen 95(20): 2349-2354
Sokka, T.; Pincus, T. 2003: A historical perspective concerning population-based and clinical studies of early arthritis and early rheumatoid arthritis Clinical and Experimental Rheumatology 21(5 Suppl 31: S5-14
Lafuente Gormaz, C.; Terrancle de Juan, I.; Broseta Viana, L. 2003: Cardiac troponins and their current clinical application Medicina Clinica 120(10): 389-394
Dwyer, C.P.; McKenna-Plumley, P.E.; Durand, H.; Gormley, E.M.; Slattery, B.W.; Harney, O.M.; MacNeela, P.; McGuire, B.E. 2017: Factors Influencing the Application of a Biopsychosocial Perspective in Clinical Judgement of Chronic Pain: Interactive Management with Medical Students Pain physician 20(6): E951-E960
Hayashi, N. 1985: Application of lasers to clinical medicine--current topics Nursing Technique 31(16): 2215-2216