Successful Treatment of Severe Alopecia Areata with Oral or Topical Tofacitinib
Cheng, M.W.; Kehl, A.; Worswick, S.; Goh, C.
Journal of Drugs in Dermatology Jdd 17(7): 800-803
2018
ISSN/ISBN: 1545-9616 PMID: 30005104 Document Number: 17534
Alopecia areata is an autoimmune disease involving the hair follicle with a chronic, relapsing course. Tofacitinib is Janus kinase inhibitor approved for treatment of rheumatoid arthritis that has been shown to be effective in treatment of alopecia areata. We present a case series of 11 patients with severe alopecia areata on longstanding, regular to high dose oral tofacitinib with marked hair regrowth. Additionally, we present a case of moderate to severe alopecia areata successfully treated with topical tofacitinib cream.
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