An open, multi-centre evaluation of a 5-day course of pivmecillinam in urinary tract infections in general practice
Place, C.
Pharmatherapeutica 3(1): 55-60
1981
ISSN/ISBN: 0308-051X PMID: 6275417 Document Number: 175222
There were 111 general practice patients (101 females and 10 males) with acute uncomplicated cystitis who received a 5 day course of pivmecillinam at a daily dose of 200 mg 3-times a day. Postive bacteriological cultures were found in 63 (57%) patients before treatment; 3/4 of all patients were totally symptom-free after treatment, with the post-treatment clinical symptom score falling by 94%. In those patients with a positive culture, the bacteriological cure rate was 90%. Pivmecillinam was generally well tolerated. Side-effects were reported in 8 (7%) patients and only 1 of these patients had to stop treatment prematurely.