Search for the heterogenetic Forssman antigen in human breast tumor tissue
Berdinskikh, M.S.; Pavliuchenkova, R.P.; Kiseleva, A.S.; Kulakova, A.M.; Kosiakov, P.N.
Biulleten' Eksperimental'noi Biologii i Meditsiny 92(12): 710-711
1981
ISSN/ISBN: 0365-9615 PMID: 7326421 Document Number: 174053
The complement fixation test was used to examine 80 human mammary tumors for the presence of heterogeneous Forssman antigen: 62 cases of cancers of different malignancy (adenocarcinoma, solid tumors), 13 cases of fibroadenomas and 5 cases of fibrocystic mastopathies. Subject to study was also normal tissue of the mammary gland. Forssman antigen was not found in all the tumors tested, as it was not detected in tissues of the normal mammary gland. Therefore the process of transformation of normal cells to tumor ones is not accompanied by the occurrence in them of heterogenous Forssman antigen.