Clinical importance of the electron microscopic study of muscle biopsies in myasthenia during prednisolone therapy
Pal'tsev, M.A.; Popova, L.M.
Arkhiv Patologii 43(1): 52-58
1981
ISSN/ISBN: 0004-1955 PMID: 7213083 Document Number: 173857
An observation of a patient with malignant generalised myasthenia treated for 5 years with surgical methods (thymectomy, glomectomy) as well as with ACTH, immunosuppressors and prednisolone is described. Before prednisolone therapy and 2 years after it muscle biopsies were taken to control the effectiveness of the therapy given. Electron microscopic examination of the second biopsy revealed predominance of muscle regeneration processes over atrophy and destruction in the absence of clinical signs of recovery.