Presence of estrogen-binding systems in the plasma membranes of rat uterus cells
Sergeev, P.V.; Denisov, I.P.; Suleĭmanov, S.S.
Farmakologiia i Toksikologiia 44(4): 429-432
1981
ISSN/ISBN: 0014-8318 PMID: 7286201 Document Number: 173690
Steroid hormone binding by plasma membranes of rat uterine cells was studied. Estradiol and estriol were shown to be bound by a specific-saturated membrane component with a high affinity for estrogens. Netrophic corticosterone and testosterone interacted with an unsaturated membrane component. It is concluded that the saturated component is necessary for primary recognition of female hormones by uterine target cells.
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