Cystadenoma of the pancreas. Study of the angiogenesis and the associated diseases
Warter, J.; Walter, P.; Warter, A.; Bareiss, P.; Sibilly, A.
La Semaine des Hopitaux Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 57(11-12): 529-537
1981
ISSN/ISBN: 0037-1777 PMID: 6261331 Document Number: 173450
We describe a case of pancreatic cystadenoma (PC) concerning a 66 year-old woman. This PC was a highly vascular cystic tumor, with typical signs: pulsatile tumor, systolic epigastric souffle and demonstrative phonangiography; the selective angiography revealed a hypervascular mass. Microscopically, tiny cysts lined by small, cuboid and columnar cells containing no glycogen, and numerous capillaries. With this case and 210 cases from the literature, two problems have been studied in this paper: the problem of the vascularity of the PC and the problem of the associated diseases. The vascularity allows to distinguish two types of PC: PC with hypervascular pattern and hypo- or avascular PC. The study of the associated diseases shows the high incidence of the tumors (23%), benign and malignant (13%) and of the cysts in other organs (5%). Comparison with polycystic disease of the kidney and the Von Hippel-Lindau disease and hypothesis concerning angio-genesis and cystogenesis in the PC are discussed.