Granulomatous coronary arteritis (Takayasu's disease)
Aufderheide, A.C.; Henke, B.W.; Parker, E.H.
Archives of Pathology and Laboratory Medicine 105(12): 647-649
1981
ISSN/ISBN: 0003-9985 PMID: 6118111 Document Number: 170934
The pathologic findings in two patients who died of nonspecific, granulomatous, coronary arteritis (Takayasu's disease) were studied. In one patient, the disease involved the aortic base, with extension into the aortic valve, coronary arteries, and interventricular septum, causing sudden death. Segmental involvement of the abdominal aorta produced an aneurysm. The other patient showed proximal coronary-artery involvement, with severe stenosis and resulting acute myocardial infarction. Newly developed lesions were found in the splenic and renal arteries. The aortic arch was not involved in either patient.