Top Abstract Purchase Related
Home
>
Node
>
Subnode

Effect of obsidan on blood electrolyte content in toxic goiter

Shikhsaidov, I.I.

Problemy Endokrinologii 27(4): 3-6

1981

ISSN/ISBN: 0375-9660
PMID: 6895254
Document Number: 169965
The effect of obsidan, mercazolil and their combinations on the plasma and erythrocytic potassium and sodium content as well as on the plasma calcium and magnesium concentration was studied under clinical conditions in 107 patients with a visceropathic stage of toxic goitre. Obsidan was given orally in a dose of 1.5 to 2 mg/kg and mercazolil in a dose of 0.5 mg/kg daily within 10 successive days. Obsidan treatment led to an increase in plasma and erythrocytes of the potassium concentration and plasma magnesium content, while the level of sodium in plasma and erythrocytes as well as of plasma calcium reduced. Mercazolil treatment (control group) exerted no significant effect on the test characteristics. It is concluded that obsidan effect on the blood calcium and sodium concentration is mediated through its action on the renin-angiotensin-aldosterone system.

Document emailed within 1 workday
Secure & encrypted payments

Sivachenko, T.P.; Krivitskiĭ, D.I. 1979: Change in the thyroid hormone content of the blood in toxic goiter in the process of surgical treatment Klinicheskaia Khirurgiia 1979(12): 6-8
Sushko, S.P. 1981: Gluco- and mineralocorticoid function of the adrenal cortex and electrolyte metabolism in euthyroid and toxic goiter Vrachebnoe Delo 4: 60-62
Baranov, V.G.; Potin, V.V.; Stepanov, G.S.; Shliakhtina, L.G. 1970: Characteristics of the biological effect of the thyrotropic activity of the blood of diffuse toxic goiter patients Problemy Endokrinologii 16(6): 27-33
Sushko, S.P. 1981: Mineralocorticoid function of the adrenal cortex and electrolyte metabolism in patients with euthyroid and toxic goiter during the early postoperative period Klinicheskaia Khirurgiia 12: 1-3
Matspanova, O.D.; Vlasova, L.I.; Koroleva, A.M.; Sidorova, I.S. 1972: Changes in the phosphorus compound and electrolyte content of the blood during pregnancy and labor under the effect of drugs with tonomotoric action: vetrasine and ATP Voprosy Okhrany Materinstva i Detstva 17(9): 70-73
Zhukovskiĭ, M.A.; Zubovskiĭ, G.A.; Toritsina, L.K.; Leonova, L.N. 1981: Serum thyrocalcitonin and parathyroid hormone content in children with diffuse toxic goiter and hypothyroidism Problemy Endokrinologii 27(3): 16-19
Kryshkova, A.M.; Kharizanova, M.S.; Dishliev, V.D. 1970: Blood pyruvic acid levels in patients with nontoxic and toxic goiter Problemy Endokrinologii 16(3): 15-17
Matiushichev, V.B.; Shamratova, V.G. 2006: Age-related specificity of the blood picture in females with diffuse toxic goiter Klinicheskaia Laboratornaia Diagnostika 2006(10): 39-42
Borodina, L.V. 1987: Amino acid composition of the blood in patients with diffuse toxic goiter during conservative therapy Terapevticheskii Arkhiv 59(6): 100-103
Cheren'ko, M.P. 1972: Development of primary diffuse toxic goiter in a patient previously subjected to surgery for euthyroid nodular goiter Klinicheskaia Khirurgiia 9: 72-73
Sikorski, R.; Paszkowski, T.; Sławiński, P.; Szkoda, J.; Zmudzki, J.; Skawiński, S. 1989: The intrapartum content of toxic metals in maternal blood and umbilical cord blood Ginekologia Polska 60(3): 151-155
Zaripova, Z.K. 1978: Interrelationship of a glucose tolerance disorder and the lipid level in the blood in diffuse toxic goiter during the treatment process Sovetskaia Meditsina 6: 56-59
Jaruga-Dolińska, E.; Zembrzuska, Z.; Korman, E. 1971: Dynamics of PBi behavior in blood serum of patients with Graves-Basedow disease and toxic nodular goiter during treatment with methimetazole Endokrynologia Polska 22(6): 535-543
Dmitriev, A.A.; Khishtovani, A.I.; Iakunin, G.A.; Kormer, A.I. 1986: Effect of hemosorption and the separate and combined use of obsidan, trental and colpharit on rheological and hemostatic properties of the blood in patients with unstable stenocardia Terapevticheskii Arkhiv 58(5): 68-73
Derwahl, M. 1999: Mutations in the thyrotropin receptor gene in the pathogenesis of toxic thyroid adenomas, toxic goiter nodules and autosomal dominant hyperthyroidism Zeitschrift für Arztliche Fortbildung und Qualitatssicherung 93(Suppl 1): 25-28
Grigor'eva, L.P.; Stroev, E.A.; Dubinina, I.I. 1982: Free amino acid spectrum and cathepsin activity in the blood serum of patients with diabetes mellitus combined with diffuse toxic goiter Problemy Endokrinologii 28(3): 13-16
Zaripova, Z.K.; Orkodashvili, L.S.; Alekseeva, G.G. 1973: Blood level of sugar, free fatty acids and immunoreactive insulin in patients with diffuse toxic goiter during a course of glucose tolerance test Problemy Endokrinologii 19(6): 13-16
Lipets, A.I.; Dozorets, I.L.; Seleznev, L.E. 1971: Dynamics of some indices of the glucocorticoid function of the adrenal cortex in patients with a severe form of diffuse toxic goiter under the effect of radioiodine treatment Sovetskaia Meditsina 34(9): 63-65
Tie, B.R.; Niu, F.X. 1993: The effect of processing on the content of toxic constituent arsenic in magnetitum Zhongguo Zhong Yao Za Zhi 18(4): 217-8 254
Zaremba, S.; Gwóźdź, H.; Banach, M. 1987: Effect of lectin from Phaseolus vulgaris (PHA-M) on the glucose content in the blood and the content of glycogen in the mouse liver and muscles Folia Biologica 35(1-2): 3-12