Compensation mechanisms for experimental reduction of the functional capacity in the guinea pig placenta. I. Changes in the maternal and fetal placenta vascularization
van der Heijden, F.L.
Acta Anatomica 111(4): 352-358
1981
ISSN/ISBN: 0001-5180 PMID: 7324862 Document Number: 169770
After experimental reduction of its functional capacity, the placenta of the guinea pig was studied microscopically for changes in the maternal and fetal vascularization pattern which could be interpreted as a compensation for this reduction. The functional capacity was reduced in 4 ways. In the experimental groups the volume density of fetal capillaries in the labyrinthine part of the placenta was increased significantly compared with untreated controls. The surface density of these vessels remained the same as in the control placentas. The volume density and surface density of the maternal lacunae did not change significantly. After experimental reduction of its functional capacity the only structural modification in the guinea pig placenta involving the maternal and fetal vascularization, which can be interpreted as a compensation mechanism, is a widening of the fetal capillaries in the labyrinth.