Glomerulonephritis in a patient with sarcoidosis. Report of a case and review of the literature
Goldszer, R.C.; Galvanek, E.G.; Lazarus, J.M.
Archives of Pathology and Laboratory Medicine 105(9): 478-481
1981
ISSN/ISBN: 0003-9985 PMID: 6895019 Document Number: 169541
A 38-year-old woman who had severe impairment of renal function displayed crescentic glomerulonephritis on a renal biopsy specimen. Chest roentgenogram showed bilateral hilar adenopathy. A biopsy specimen of a hilar lymph nodes showed many noncaseating granulomas, consistent with sarcoidosis. Therapy with plasmapharesis, cyclophosphamide, and corticosteroids was associated with improvement of renal function and disappearance of hilar adenopathy. Based on this case and a review of the literature, sarcoidosis should be considered when studying crescentic glomerulonephritis.