Relationship between Cardio-Ankle Vascular Index (CAVI) and Obstructive Sleep Apnea (OSA)

Romsaiyut, S.; Chotnaiyawattrakul, W.; Boonyasirinant, T.

Journal of the Medical Association of Thailand 98(2): 156-162


ISSN/ISBN: 0125-2208
PMID: 25842796
Document Number: 16829
A non-invasive test called Cardio-Ankle Vascular Index (CA VI) measures aortic stiffness, which is an early sign of atherosclerosis. Obstructive sleep apnea (OSA) has a close association with cardiovascular mortality and morbidity. We sought to assess the relationship between OSA and arterial stiffness. Seventy-one patients with OSA (apnea-hypopnea index AHI ≥ 5, mean age 51.5 ± 14.1 years, 27 females) and 11 controls (AHI < 5, mean age 56.8 ± 11.8 years, 5 females) were enrolled in the study. In all subjects, arterial stiffness (CAVI) was performed and recorded along with blood pressure, pulse pressure of brachial arteries, and ankle arteries. The demographic data of the patients with OSA and controls were not significantly different. Subjects with OSA demonstrated higher values ofmean ankle artery pulse pressure than the controls (73.1 ± 14.6 vs. 59.6 ± 6.1 mmHg, respectively), but arterial stiffness and CAVI had no statistically significant difference (7.47 ± 1.68 vs. 7.25 ± 1.61, respectively). There was no relationship between arterial stiffness CAVI, and the presence of OSA. However; there was a significant association between ankle artery pulse pressure and the presence of OSA.

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Relationship between Cardio-Ankle Vascular Index (CAVI) and Obstructive Sleep Apnea (OSA)