Influence of measurement time and reacton medium on kinetic immunturbidimetric protein determination
Müller-Matthesius, R.; Opper, C.
Journal of Clinical Chemistry and Clinical Biochemistry 18(8): 501-510
1980
ISSN/ISBN: 0340-076X PMID: 7411029 Document Number: 167921
For fixed-time rate analysis the turbidity curve, which is the reference system of immunturbidimetric protein determination, depends on the time of 1st measurement, on the subsequent measurement time interval and on the composition of the reaction medium. The IgG/anti-IgG system was chosen as an example to demonstrate how the reaction parameters can be optimized. In this context particular consideration was given to some of the analyzers commonly used in larger laboratories (ABA-100, CentrifiChem, Cobas Bio, GEMSAEC, Gilford 3500).