Operable carcinoma of the breast. Prognostic value of estradiol receptors. Preliminary report

Cheix, F.; Biron, A.; Bailly, C.; Mayer, M.; Pommatau, E.; Saez, S.

La Nouvelle Presse Medicale 9(13): 933-935

1980


ISSN/ISBN: 0301-1518
PMID: 7360626
Document Number: 167624
151 women were treated for potentially curable breast cancer. Their tumors were routinely analysed for estrogen receptors by the dextran-coated charcoal technic. Data were analyzed in relation to several parameters: age, age of menstruation, menopausal status, tumor size, TNN staging, axillary node status, nature of treatment. We have examined the pronostic implication of an ER negative content (ER-) in the primary tumor. We have found that the absence of detectable estrogen receptor in primary breast tumor appears to be correlated with a short disease free interval. In positive axillary node patients the value of the disease free interval is significantly shorter in ER- than in ER+ group: 11.5 months versus 23.5 (p less than 0.01).

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