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Localization and restriction mapping of the origin of replication of rat liver mitochondrial DNA

Tomarev, S.I.; Zakhar'ev, V.M.; Zl'darov, M.A.

Biokhimiia 45(10): 1909-1912

1980

ISSN/ISBN: 0320-9725
PMID: 6263363
Document Number: 166366
Using plasmid pCV II, a recombinant comprising the origin of replication of rat liver mitochondrial DNA was obtained. A detailed restriction map of the region based on restrictases Hae III, Hpa II and Hind II was developed. The origin of mitochondrial DNA replication is localized in one of the Hind II fragments.

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