Use of Ceporin after a cadaveric kidney allograft
Bogomolova, N.S.; Goriainov, V.A.; Vinogradova, L.N.
Antibiotiki 25(4): 299-302
1980
ISSN/ISBN: 0003-5637 PMID: 6989323 Document Number: 165817
Cephaloridin (ceporin of "Pliva", Yugoslavia) was used in the treatment of patients after allotransplantation of the kidney from a cadaver during the early postoperative period with a purpose of prevention (5 patients) and therapy of complications, such as pneumonia (7 patients), sepsis (3 patients), pyelonephritis of the transplanted kidney (4 patients). The drug levels in the blood serum and urine were determined 1, 2, 4, 6, 8 and 24 hours after the administration. The drug was used with regard for the transplant function estimated by the data of the glomerular filtration and concentration of the nitrous residues in the blood. The antibiotic dose depended on the transplant function. The study provided some recommendations as for the ceporin use in therapy of such population of patients.