Assessment of the loss of thyroid hormone during hemodialysis by administration of a hormone tracer in an in vitro experiment
Beyer, H.K.; Schuster, P.; Pressler, H.
Nuklearmedizin. Nuclear Medicine 19(6): 294-298
1980
ISSN/ISBN: 0029-5566 PMID: 7279679 Document Number: 165254
Several investigators have examined thyroid function in hemodialysis patients. Similar results were obtained: reduced total triiodothyronine and subnormal thyroxine values in serum. This raised the question whether a deficiency in hormones during hemodialysis could be responsible for these findings. The present studies were ade in an attempt to prove or disprove this assumption by determining hormone loss. The loss of thyroxine during hemodialysis was 1.1 microgram. This order of magnitude excludes a hormone deficit caused by dialysis. The assumption that an increased loss of hormone during hemodialysis is the cause of pathologic changes in the serum as compared with the period before dialysis can be considered as disproved.