Dynamic study of antidiuretic hormone during benign mineralocorticoid and metacorticoid hypertension
Marchetti, J.; Thibonnier, M.; Gonzales, M.F.; Corvol, P.; Menard, J.
Acta Endocrinologica 95(4): 444-453
1980
ISSN/ISBN: 0001-5598 PMID: 7456975 Document Number: 164797
Deoxycorticosterone characteristic of DOC-induced benign hypertension even in the absence of Na from drinking water. There are 2 possible mechanisms through which ADH might raise BP: by expanding plasma volume and by acting as a vasoconstrictor agent directly affecting the arterial walls. However, vasopressin does not seem necessary to maintain hypertension, since ADH excretion was normal during the metacorticoid phase.