Effect of ouabain on 3H-epinephrine washout from the adrenal gland
Baskin, S.I.; Kendrick, Z.V.; Goldfarb, A.; Roberts, J.; Zaydon, A.C.
Research Communications in Chemical Pathology and Pharmacology 29(2): 365-368
1980
ISSN/ISBN: 0034-5164 PMID: 7414054 Document Number: 164760
Epinephrine release from the adrenal medulla can sensitize the heart to arrhythmias. The effects of ouabain on epinephrine release was studied in cats. Ouabain, a Na-K-ATPase inhibitor, may enhance adrenal release of epinephrine by inhibiting a Na-pump. Ouabain-induced arrhythmias may be due, in part, to increased adrenal epinephrine release.
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