Structure of the carbohydrate moiety of carminomycins II and III
Spiridonova, I.A.; Lomakina, N.N.; Vlasova, T.F.
Antibiotiki 25(8): 563-566
1980
ISSN/ISBN: 0003-5637 PMID: 6250463 Document Number: 164642
Saccharides II and III were obtained on catalytic hydrogenolysis of carminomycins II and III. The saccharides contained daunosamine and a N-free fragment of unknown structure. Crotonic aldehyde in the form of 2,4-dinitrophenylhydrazone and 1,2-propylenglycol in the form of 3,5-dinitrobenzoate were isolated on acid hydrolysis of the saccharides. The study on the chemical and spectral properties (PMR spectra) of the saccharides, their N,O-acetates and hydrolysis products suggested the structure of the carbohydrate moiety of carminomycins II and III as a disaccharide of daunosamine and acyclic semiacetal of 2,4-desoxytetrose.