The influence of hemolysis on capillary blood plasma density measurements using the mechanical oscillator technique
Hinghofer-Szalkay, H.; Wurm, H.
Journal of Clinical Chemistry and Clinical Biochemistry 18(10): 615-619
1980
ISSN/ISBN: 0340-076X PMID: 7441171 Document Number: 164265
Sampling of capillary blood often yields slightly hemolytic plasma. We investigated the influence of hemolysis on plasma density using the mechanical oscillator technique. Plasma density rose by approximately 0.1 milligram when the hemoglobin content increased by 0.5 milligram. These values correspond to 0.3% hemolysis and were not exceeded in more than 70% of the investigated capillary plasma samples. In general, hemolysis must be taken into account if plasma density measurements are to be made with an accuracy better than 0.5 milligram, which corresponds to 2-3% of the plasma protein content.