Dihydrostreptomycin toxicity in the Mongolian gerbil, Meriones unguiculatus

Wightman, S.R.; Mann, P.C.; Wagner, J.E.

Laboratory Animal Science 30(1): 71-75

1980


ISSN/ISBN: 0023-6764
PMID: 6157053
Document Number: 164263
A fatal syndrome of acute toxicity was produced in Mongolian gerbils following the injection of a penicillin-dihydrostreptomycin-procaine combination. The toxicity was determined to be due to the dihydrostreptomycin component. Fifty milligrams of dihydrostreptomycin produced 80-100% mortality in 55-65 g gerbils.

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