Guillain - Barre' syndrome following recombinant hepatitis B vaccine and literature review
Sinsawaiwong, S.; Thampanitchawong, P.
Journal of the Medical Association of Thailand 83(9): 1124-1126
2000
ISSN/ISBN: 0125-2208 PMID: 11075984 Document Number: 1640
A 17 year-old woman developed progressive quadriparesis with bilateral facial diplegia after immunization with recombinant hepatitis B vaccine 3 days prior. Cerebrospinal fluid analysis revealed acellular fluid with high protein level. The electrodiagnosis was compatible with demyelinating polyneuropathy. Other potential causes of Guillain-Barre' syndrome (GBS) were ruled out. Her motor power gradually improved and returned to normal later. The temporal relationship between GBS and vaccination was suggestive of a vaccine-induced cause. Mechanisms of this very rare complication are proposed with a literature review.
Document emailed within 1 workday
