Drug trials: treatment of urinary tract infection with multiple-dose intramuscular administration of cephamandole

Nankervis, A.; Fairley, K.F.; Shaw, P.; Whitworth, J.A.; Miles, H.; Graham, I.; Pavillard, R.

Medical Journal of Australia 1(9): 427-428

1980


ISSN/ISBN: 0025-729X
PMID: 7393095
Document Number: 163420
Therapy with cephamandole (1.0 g, every eight hours) for five days was effective in eliminating cephamandole-sensitive microorganisms from the urinary tract. A 75% cure rate was achieved in a group of 20 patients, 45% of whom had abnormalities of the urinary tract. Local pain (despite addition of lignocaine) was sufficiently prolonged and severe to make multiple-dose intramuscular administration unacceptable. No other toxic effects were encountered.

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