A possible common pathogenesis of the mesangial IgA glomerulonephritis in patients with Berger's disease and Schönlein-Henoch syndrome
Egido, J.; Sancho, J.; Mampaso, F.; Lopez Trascasa, M.; Sanchez Crespo, M.; Blasco, R.; Hernando, L.
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association 17: 660-666
1980
ISSN/ISBN: 0071-2736 PMID: 7017703 Document Number: 163243
High serum levels of polymeric IgA, partially as immune complexes, have been found in patients with Berger's disease and Schönlein-Henoch syndrome. Polymeric IgA was also found in the renal mesangium in both entities as judged by its affinity for the human secretory component. These data reinforce the clinical and morphological suspicion that both entities may represent variations of the spectrum of the same disease.