Criticism of the K value-utility and evidence of the glucose assimilation coefficient
Möricke, R.; Caruso, M.; Andraczek, F.
Zeitschrift für die Gesamte Innere Medizin und ihre Grenzgebiete 35(8): 325-330
1980
ISSN/ISBN: 0044-2542 PMID: 7434841 Document Number: 162077
Theoretical statements concerning the calculation of the K-value and explanations of the practical approach in the estimation of the K-value are the initial position. It is proved that it is not possible after a standardized glucose supply to establish by means of the K-value a true gradation of the glucose assimilation, which is independent on the population and lies on an absolute proportion scale, of any test persons on various conditions. Up to now this fact is not taken into consideration when the K-value is used and judged for the characterization of the glucose assimilation and leads to weighty errors in the kinetic evaluation of the measuring data. Since both the height of the fasting blood glucose and the speed of the glucose elimination are included as diagnostic separation criteria in the K-value, it is, on the other hand, well suited for the delimitation of latent, asymptomatic and manifest diabetics from persons with healthy metabolism.