Acute generalised exanthematous pustulosis (AGEP) -a potential pitfall for the acute physician

Cranga, T.A.; Simpson, M.A.; Featherstone, P.

Acute Medicine 15(3): 140-144

2016


ISSN/ISBN: 1747-4892
PMID: 27759749
Document Number: 16186
Acute generalised exanthematous pustulosis is a rare drug-induced dermatosis with an incidence of 1-5 cases per million cases per year, characterised by the appearance of hundreds of sterile pustules over erythematous and oedematous skin. Fever and neutrophilia are usually present. It has a rapid course and usually resolves following discontinuation of the precipitating drug or as a result of topical corticosteroid treatment. A patient with AGEP, who presented with generalized pustulosis lesions after the use of Flucloxacillin for cellulitis is described, along with the management and differential diagnosis of this condition.

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Acute generalised exanthematous pustulosis (AGEP)-a potential pitfall for the acute physician