Liver zinc uptake, influence of glucocorticoids and its chronology
Rodríguez de la Nuez, A.L.; Sierrasesúmaga, L.; Monreal, I.; Pérez Afonso, F.; De Pablo, P.; Villa Elízaga, I.
Anales Espanoles de Pediatria 13(12): 1079-1084
1980
ISSN/ISBN: 0302-4342 PMID: 7013590 Document Number: 161098
A study on the effect of glucocorticoids in the hepatic uptake of zinc in experimental animals (Norway rats, Wistar strain) is presented. Liver zinc levels were measured in fresh and frozen tissue samples. A significant increase was seen in the liver zinc of prednisolone treated rats. This increase is more marked in the first ten days of glucocorticoid intake. Authors consider that this data support the hypothesis of a hormonal control in liver zinc metabolism.