"Ecdysis" secondary to 5-fluorouracil
Yaffee, H.S.; Grots, I.
Cutis 25(6): 649-650
1980
ISSN/ISBN: 0011-4162 PMID: 7379597 Document Number: 160828
The use of 5-fluorouracil in three patients with basal cell carcinoma was followed by a peculiar necrosis which, when curetted, shelled out completely like a snake skin. We have termed this "ecdysis." Histologic examination revealed tumor necrosis, leukocytes, and fibrin. There have been no recurrences to date.
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