Regeneration of liver with experimental cirrhosis after 4 resections
Solopaev, B.P.; Bobyleva, N.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 90(10): 483-485
1980
ISSN/ISBN: 0365-9615 PMID: 7426715 Document Number: 160639
The capability of the liver with experimental cirrhosis to regenerate after four resections was disclosed by histological, histochemical, stereometric and biochemical analyses. The liver with pathological changes was found to be capable of regenerating after repeated resections which resulted in the removal of liver tissue exceeding 1.5-fold the normal liver weight. During regeneration of the liver with pathological changes a tendency was recorded to parenchymal normalization, to a decrease in the amount of excessive connective tissue, and to an increase in the liver weight after every resection. The degree of the mitotic activity of hepatocytes and that of binuclei were different after some repeated resections.