Loss of 2 kidney grafts due to recurrence of type Ii membrano-proliferative glomerulonephritis
Leumann, E.P.; Briner, J.; Fierz, W.; Largiadèr, F.
Schweizerische Medizinische Wochenschrift 110(11): 408-413
1980
ISSN/ISBN: 0036-7672 PMID: 6988957 Document Number: 160621
Recurrent glomerulonephritis after renal transplantation is seen in a very high percentage of patients with dense "deposit" disease (= membrano-proliferative glomerulonephritis type II). However, loss of graft due to recurrence is rare; only 4 cases have been reported. Two additional pediatric patients are described. Both had recurrent dense "deposit" disease with extracapillary proliferation and crescent formation. In one of them, a quiet initial phase of 20 months was followed by an extremely rapid progression of the disease leading to loss of graft function within 3 weeks.