Causes of a nitrogen balance disorder in patients with cancer of the large intestine
Fedotov, I.L.; Gegenava, A.P.; Buttaev, R.M.
Voprosy Onkologii 26(10): 52-55
1980
ISSN/ISBN: 0507-3758 PMID: 7434679 Document Number: 160315
Assays were made of blood serum proteins, final N products of urine and feces in 115 patients with colonic cancer and in 19 patients with polyposis. The N balance was studied in 59 rectal cancer patients prior to and after operation. In a group of patients with the malignant tumor the endogenic protein hyperexcretion was found as well as a reduced serum proteins level and an associated dependence of hypoproteinemia on the degree of their loss with feces. A negative N balance was noted in patients with cancer. Surgical intervention and purulent infection may aggravate this condition. The radical treatment of colonic cancer results in a gradual normalization of N-protein metabolism.