Epidemiological evaluation of thromboembolic risk. Critical review of the prospects offered by determination of antithrombin III
Gabrielli, L.; Lorenzi, G.; Sarcina, A.; Rossi, E.; Margstakler, E.; Mondonico, P.
Minerva Medica 71(2): 83-88
1980
ISSN/ISBN: 0026-4806 PMID: 7354931 Document Number: 159635
Authors review the epidemiology of deep venous thrombosis and the prothrombotic state in high risk patients; particularly antithrombin III role in blood clotting is considered. A fall in antithrombin III concentration and/or activity can induce hypercoagulability and thrombosis. Moreover authors stress the need to evaluate antithrombin III as anti-Xa activity, to detect high risk patients for deep venous thrombosis.