Determination of extractable mirex in whole blood
Stahr, H.M.; Hyde, W.; Gaul, M.
Journal - Association of Official Analytical Chemists 63(5): 965-969
1980
ISSN/ISBN: 0004-5756 PMID: 7410307 Document Number: 159401
A method for the determination of free mirex in blood has been developed in which whole blood is extracted with acetone–hexane (9+91), passed through Na2SO4, concentrated, and analyzed by electron capture gas-liquid chromatography (GLC). Results were highest for fresh blood. Recoveries were verified by determining 14C-labeled mirex before and after extraction. Little mirex was detected in the samples after extraction. Hydrolysis of residual blood indicates that a metabolite of mirex is released. The possible metabolite has a CLC retention time and mass spectrum which resemble hydroxy metabolites of mirex.