Update on the management of severe traumatic brain injury

Oddo, M.; Gasche, Y.

Revue Medicale Suisse 5(229): 2506-2510

2009


ISSN/ISBN: 1660-9379
PMID: 20084870
Document Number: 15925
Prognosis after severe traumatic brain injury (TBI) is determined by the severity of initial injury and secondary cerebral damage. The main determinants of secondary cerebral damage are brain ischemia and oedema. Traumatic brain injury is a heterogeneous disease. Head CT-scan is essential in evaluating initial type of injury and severity of brain oedema. A standardised approach based on prevention and treatment of secondary cerebral damage is the only effective therapeutic strategy of severe TBI. We review the classification, pathophysiology and treatment of secondary cerebral damage after severe TBI and discuss the management of intracranial hypertension, cerebral perfusion pressure and brain ischemia.

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Update on the management of severe traumatic brain injury