Urinary magnesium and its relationship to calcium in recurrent stone-formers and controls
Leskovar, P.; Hartung, R.; Siebert, A.; Wellnhofer, E.
Der Urologe. Ausg. a 19(4): 214-219
1980
ISSN/ISBN: 0340-2592 PMID: 7414766 Document Number: 158486
Over a period of 4--6 weeks, urine samples were collected three times daily in a group of 16 recurrent stone-formers and in a control group of 11 healthy persons and the urinary concentrations of magnesium, calcium, ionized calcium and creatinine were determined. The Mg-concentrations were distinctly lower in the group of recurrent stone-formers than in the group of healthy controls. The differences were clearly present also in the ratio Ca/Mg, but were diminished in the Mg/creatinine ratio. The Ca2+/Mg-ratio was significantly raised in the group of recurrent stone-formers (p < 0.01) because of the significantly increased Ca2+-concentration and the diminished Mg-concentration in the group of stone-patients. The correlation between the Ca-resp. Ca2+-concentration and the Mg-concentration was in both groups, in the patient and control group, high (r about 0.7).