Vinblastine, intermittent bleomycin, and single-dose cis-dichlorodiammineplatinum (II) in the management of stge III testicular cancer
Bosl, G.J.; Kwong, R.; Lange, P.H.; Fraley, E.E.; Kennedy, B.J.
Cancer Treatment Reports 64(2-3): 331-334
1980
ISSN/ISBN: 0361-5960 PMID: 6157467 Document Number: 158349
A program for treating advanced testicular cancer with vinblastine, bleomycin and a single dose of cis-dichlorodiammineplatinum(II) was used to reduce the toxicity of a 5-day regimen while maintaining a high response rate. In 10 previously untreated and 6 previously treated patients, the complete remission rate was 25%. Toxic reactions were frequent; there was 1 drug-related death. This single-dose cis-dichlorodiammineplatinum(II) program is ineffective in the treatment of testicular cancer. Other means for reducing toxicity will have to be considered.