Energy dispersive x-ray detection of thorium dioxide
Bowen, J.H.; Woodward, B.H.; Mossler, J.A.; Ingram, P.; Shelburne, J.D.
Archives of Pathology and Laboratory Medicine 104(9): 459-461
1980
ISSN/ISBN: 0003-9985 PMID: 6932191 Document Number: 158119
Since the recognition of the development of certain malignant neoplasms in association with thorium dioxide (Thorotrast), its presence has been documented by light microscopic appearance and time-consuming autoradiography. Energy dispersive x-ray microanalysis can be used in the rapid documentation of thorium in paraffin-embedded tissues and it is confirmed that thorium is the principal component of the granular deposits described by light microscopy.