Effect of tolbutamide on plasma renin activity
Sherma, N.K.; Gossain, V.V.; Michelakis, A.M.; Rovner, D.R.
American Journal of Physiology 236(1): E1-E3
1979
ISSN/ISBN: 0002-9513 PMID: 219704 Document Number: 152656
The effect of tolbutamide on renin secretion in rats was studied in vivo and in vitro. Administration of tolbutamide in doses of 12.5 and 25 mg/kg body wt i.p. to 2 groups of rats produced no significant change in plasma renin activity compared to the control group. In the in vitro experiments renal cortical slices were incubated with increasing concentrations of tolbutamide (0-4 mg/ml). No significant increase in the net renin production was observed, whereas the concentration of cyclic.
Document emailed within 1 workday
Related Documents
Odum, C.U. 1994: Studies of the effect of mode of delivery: obstetric analgesia and anaesthesia on maternal Plasma Renin Concentration (PRC) and Plasma Renin Activity (PRA) in the normotensive and hypertensive primigravidae West African Journal of Medicine 13(1): 1-6Klumpp, F.; Klaus, D. 1978: Effect of oral contraceptives on the capacity to stimulate plasma renin activity and plasma aldosterone Die Medizinische Welt 29(6): 228-231
Ocón, J.; Piña, C.; Castellet, R.; Vila, R.; del Río, G.; Arnau, C. 1985: Clinical evaluation of penbutolol (Hoe 893d) (beta adrenergic blocker), alone and in combination with hydrochlorothiazide, in the treatment of arterial hypertension. II. Effect on plasma electrolytes, renal function, plasma renin and aldosterone activity and risk factors, including plasma lipids Medicina Clinica 85(2): 53-57
Larochelle, P.; Genest, J.; Kuchel, O.; Boucher, R.; Gutkowska, Y.; McKinstry, D. 1979: Effect of captopril (SQ 14225) on blood pressure, plasma renin activity and angiotensin I converting enzyme activity Canadian Medical Association Journal 121(3): 309-316
Pratt, J.H.; Luft, F.C. 1979: The effect of extremely high sodium intake on plasma renin activity, plasma aldosterone concentration, and urinary excretion of aldosterone metabolites Journal of Laboratory and Clinical Medicine 93(5): 724-729
Vacca, G.; Chiorboli, E.; Grossini, E.; Papillo, B. 1994: The effect of distension of the stomach on plasma renin activity in the anesthetized pig Cardioscience 5(4): 261-267
Kaul, C.L.; Grewal, R.S. 1976: Effect of some antihypertensive drugs and catecholamine depletors on the plasma renin activity in the rat Archives Internationales de Pharmacodynamie et de Therapie 224(1): 91-101
Brandes, J.M.; Abramovici, H.; Katz, M.; Diengott, D.; Spindel, A.; Kahana, L. 1978: The effect of postural changes on plasma renin activity during normal and pathologic pregnancies Obstetrics and Gynecology 52(5): 530-532
Yamada, A. 1977: Effect of alpha and beta-adrenergic blockades on plasma renin activity Nihon Jinzo Gakkai Shi 19(5): 311-319
Musumeci, V.; Baroni, S.; Cardillo, C.; Zappacosta, B.; Zuppi, C.; Tutinelli, F.; Folli, G. 1987: Cardiovascular reactivity, plasma markers of endothelial and platelet activity and plasma renin activity after mental stress in normals and hypertensives Journal of Hypertension. Suppl: Official Journal of the International Society of Hypertension 5(5): S1-S4
Lall, S.B.; Peshin, S.S.; Karmarkar, M.G. 1995: Plasma renin activity in normal healthy volunteers: effect of physiological variables Indian Journal of Physiology and Pharmacology 39(1): 51-54
Muñiz Grijalvo, O.; Carneado de la Fuente, J.; Villar Ortiz, J.; Lapetra Peralta, J.; Molina Miró, J. 1991: The influence of changes in the blood pressure and plasma renin activity on the natriuretic effect of nifedipine Medicina Clinica 96(17): 645-648
Balansard, P.; Chabrillat, Y.; Paulin, R.; Libes, M.; Gérard, R. 1977: Effect of atenolol, a new cardioselective beta-blocker, on plasma renin activity in treatment of hypertension Acta Cardiologica 32(4): 229-243
Iwai, M.; Senba, I.; Kanno, H.; Nakaoka, H.; Inaba, S.; Horiuchi, M. 2012: Renin Inhibitors Inhibited the Activity of Recombinant Human Renin but not Activity in Healthy Human Plasma Clinical Laboratory 58(3-4): 291-298
Ikonomov, O.C.; Stoynev, A.G.; Shisheva, A.C.; Tarkolev, N.T. 1985: Effect of constant light and darkness on the circadian rhythms in rats. II. Plasma renin activity and insulin concentration Acta Physiologica et Pharmacologica Bulgarica 11(1): 55-61
Iacobelli, A.; Maceroni, P.; Fontana, O.; Vecci, E.; Cavallotti, C. 1975: Effect of beta-adrenergic block on the response of plasma renin activity to acute sodium depletion in the rabbit Bollettino della Societa Italiana di Biologia Sperimentale 51(18): 1133-1139
Kolber-Postepska, B.; Zebrowska-Lupina, I.; Markiewicz, M.; Horubała-Bielak, G. 1989: Effect of captopril on various components of the kinin system and plasma renin activity in patients with idiopathic arterial hypertension Kardiologia Polska 32(3): 121-130
Sonkodi, S.; Pap, A.; Varró, V. 1976: Effect of the beta-receptor blocking agent visken on blood pressure of hypertensive patients, on plasma renin activity and electrolytes Therapia Hungarica 24(2): 60-62
Leonetti, G.; Bianchini, C.; Picotti, G.B.; Cesura, A.; Caccamo, L.; Marini, A. 1980: Plasma catecholamines and plasma renin activity at birth and during the first days of life Clinical Science 59 Suppl 6(153): 319s-321s
Wernze, H.; Hilfenhaus, M.; Rietbrock, I.; Schüttke, R.; Kühn, K. 1975: Plasma renin activity and plasma aldosterone during anaesthesia and operative stress and beta-adrenergic blockade Der Anaesthesist 24(11): 471-476