The carboxy-terminal peptides of in vitro precursor and in vivo mature kappa light chains are identical
Rose, S.M.; Kuehl, W.M.
Journal of Immunology 123(3): 1024-1028
1979
ISSN/ISBN: 0022-1767 PMID: 112183 Document Number: 151612
Protein structural analysis of several precursor light chains indicates that these in vitro products include a cysteine-containing tryptic peptide that is indistinguishable from the carboxy-terminal tryptic tripeptide present in in vivo mature kappa light chains. It is concluded that although in vitro precursor light chains contain an additional amino-terminal sequence, their carboxy-terminus is the same as that found in in vivo mature light chains.