Microbiological assays for antibiotics and vitamins: considerations for assuring accuracy

Kavanagh, F.; Ragheb, H.S.

Journal - Association of Official Analytical Chemists 62(4): 943-950

1979


ISSN/ISBN: 0004-5756
PMID: 387712
Document Number: 151429
Factors that may influence the accuracy and precision of microbiological manual and semiautomated turbidimetric methods as well as diffusion assays are discussed. Influence of kind of equipment, media, test bacteria, sample preparation, form of dose response lines, operations, and personnel on quality of assays is examined with the objective of reducing to insignificance those factors under control of the analyst that are responsible for low quality assays.

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