Problems of diagnosis of disseminated intravascular coagulation (DIC)
Bowie, E.J.; Owen, C.A.
Southeast Asian Journal of Tropical Medicine and Public Health 10(3): 325-327
1979
ISSN/ISBN: 0125-1562 PMID: 515796 Document Number: 151418
Acute generalized intravascular coagulation is regularly associated with fibrinolysis. Evidence of the clotting process includes thrombocytopenia, hypofibrinogenemia, prolongation of the prothrombin time (deficiency of factor V and fibrinogen) and of the partial thromboplastin time (factor VIII is also deficient). Evidence of fibrinolysis is elevation of fibrinolytic split products (FSP or FDP). A positive protamine gel results from both coagulation and fibrinolysis.