Flunisolide in chronic bronchial asthma
Webb, D.R.; Mullarkey, M.F.; Freeman, M.I.
Annals of Allergy 42(2): 80-82
1979
ISSN/ISBN: 0003-4738 PMID: 420422 Document Number: 150883
Sixteen steroid dependent and 13 steroid independent patients with bronchial asthma were treated for three months with flunisolide by aerosol. Asthma improved in these patients, other medication usage decreased and adverse side effects were minimal. A significant increase in morning plasma cortisol levels occurred in steroid dependent patients, whereas cortisol levels in steroid independent patients remained normal. An unexpected decline in response to metyrapone occurred in both groups of patients and suggests that this test is affected by flunisolide usage.