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Permeability of histohematic barriers of the small intestine during perfusion with some preserving solutions

Kulik, B.P.; Genyk, S.N.; Krysa, V.M.; Goncharenko, R.V.; Kostiuk, V.M.

Biulleten' Eksperimental'noi Biologii i Meditsiny 88(9): 286-288

1979

ISSN/ISBN: 0365-9615
PMID: 519019
Document Number: 150764
The permeability changes in histohematic barriers of the isolated small intestine loops of laboratory white rats whose vessels were perfused with 0.85% sodium chloride, Ringer-Lock, Hanks and Collins-2 solutions as well as with hemodez and aminopeptide were studied. The amount of the fluid flowing off the vessels, perfusate penetration into the intestinal lumen and its transudation through the serous membrane were determined. It was concluded that the slightest disturbance in the small intestine histohematic barrier was observed during perfusion of the vessels with Collins-2 solution. The above method is recommended for testing the comparative characteristics of the preserving solution.

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