Improvement in the primary immunization scheme for children against whooping cough, diphtheria and tetanus
Sokhin, A.A.; Kovalenko, A.I.; Kucheriavenko, V.S.; Logvinova, V.M.; Komarevskaia, R.V.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 6: 9-15
1979
ISSN/ISBN: 0372-9311 PMID: 88857 Document Number: 150675
The authors studied the reactigenic properties, immunological and epidemiological efficacy of vaccination of children aged under one year by the experimental schemes (AKDC-AKDC-K -- 1 ml, and AKDC-AKDC-K -- 0.5 ml) in comparison with the official pertussis, diphtheria, and tetanus immunization scheme. There proved to be a greater immunogenicity and a better protective effect against pertussis in vaccination according to the experimental schemes. The vaccine reactions were somewhat more incident in children vaccinated according to the AKDC-AKDC-K -- 1 ml scheme, but their essential reduction was reached with reduction of the pertussis antigen third vaccination dose to 0.5 ml.