Study of validity of pyridinoline and correlation of pyridinoline and beta crosslap in postmenopausal women
Bunyaratavej, N.; Buranasinsup, S.
Journal of the Medical Association of Thailand 94(Suppl 5): S76-S78
2011
ISSN/ISBN: 0125-2208 PMID: 22338932 Document Number: 15046
This research studied the validity and correlation of beta-CTx (Betacrosslap) and Pyridinoline (PYD) in 71 cases of postmenopausal Thai women who attended at the osteoporosis clinic. The validity consisted of sensitivity, specificity and accuracy of PYD. They were 53.44, 84.6 and 59.15% respectively. So, the validity of pyridinoline test was rather poor and the correlation between betacrosslap and pyridinoline was weak (r = 0.123, p = 0.0001) which was not significant in practice. In conclusion, the pyridinoline test was not proper for bone resorption even pyridinoline was abundant in bone.